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KMID : 1098420220300020124
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Korean Journal of Medicinal Crop Science
2022 Volume.30 No. 2 p.124 ~ p.133
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Antioxidant Activity and Non-Targeted Metabolic Profiling of Solvent Fractions of Glehnia littoralis Shoots
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Kim Chul-Joong
Jeon Ji-Hyeong
Choi Seon-Kang
Yu Chang-Yeon
Lee Jae-Geun
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Abstract
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Background: The soft petiole of the Glehnia littoralis shoot is used as a raw material for food. It contains specific ingredients such as polyacetylene and coumarin. However, basic research considering their safety verification, efficacy, and ingredient identification is needed.
Methods and Results: In this study, GC/MS compound profiling and LC/UVD were performed to evaluate the antioxidant activity of G. littoralis shoot extract fractions, and to identify the compounds contained therein. Total phenol and flavonoid content as well as antioxidant activity were maximum in the ethyl acetate layer, and a significant correlation was confirmed between total phenol content and antioxidant activity. GC/MS compound profiling, revealed a total of more than 40 compounds, and active ingredients such as coumarin-based phellopterin unique to G. littoralis and polyacetylene-based falcarinol (panaxinol) were qualitatively analyzed. The highest coumarin content was found in the ethyl acetate layer.
Conclusions: In this study, the antioxidant activity and compounds contained in the shoot (soft petiole) fractions of G. littoralis were confirmed. These basic data may contribute to expanding the material value of G. littoralis in the future.
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KEYWORD
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Glehnia littoralis F. Schmidt ex Miq., Antioxidant Activity, Coumarin, Ethyl Acetate Fractions, Non-targeting Metabolic Profiling, Shoots
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